新Duolink 抗半抗原的探針(anti- biotinylated, fluorescein conjugated or digoxin labeled)產品 時間: 2009-09-17 16:49:26
PLA probes PLUS and MINUS are divided into anti-Species and anti-Hapten.

Haptens are small molecules that can be attached to primary antibodies. The Duolink anti-Hapten product family contains PLA probes to the haptens Biotin, Fluorescein and Digoxin. The hapten modification of the primary antibody can be done in the lab, modified primary antibodies (biotinylated, fluorescein conjugated or digoxin labeled) are also available from antibody vendors.

The anti-Hapten family relieves the demand to use primary antibodies raised in different species. Two primary antibodies from the same species (e.g. mouse) can now be used in a Duolink assay, if they are modified with two different haptens. Using a split monoclonal antibody batch with two different hapten modifications, the new products also enables a new application field the possibility to detect homodimeric protein interactions.